The Institut de Neurosciences des Systèmes (INS, Director Viktor Jirsa, https://ins-amu.fr/) is a multidisciplinary research institute of Inserm and Aix-Marseille University located on La Timone Campus in Marseille, France. Inserm is the French National Institute of Health and Medical Research and its patronage prioritizes the medical orientation of INS research. Members are comprised of academic faculty and clinicians of La Timone Hospital (APHM) institutions, as well as Inserm and CNRS researchers. CNRS is the French National Institute of Scientific Research. The research program at INS is focused on understanding the complexity and dynamics of the human brain and its links to cognition, consciousness and their disorders. INS has been created with the intent to attract researchers sharing the same vision of the brain as a dynamic network and integrate experimental, theoretical and clinical approaches towards understanding brain function and dysfunction. INS researchers perform research across species ranging from the rodent to the human brain to uncover the mechanisms underlying brain function and its disorders, notably epilepsy as the paradigmatic dynamic brain disease. INS houses a wide range of state-of-the-art facilities of brain research, which includes The Virtual Brain, an important neuroinformatics platform associated with the Human Brain Project, an MEG facility, TMS-EEG with a Brain Navigation system, various electrophysiology laboratories, and an epileptic patient unit with SEEG.